Description
Sodium salicylate is a water-soluble sodium salt of salicylic acid, primarily used for its anti-inflammatory, analgesic, and antipyretic properties. It appears as a white crystalline powder and is also available in granule and liquid forms. Sodium salicylate is a non-steroidal anti-inflammatory drug (NSAID) and acts by inhibiting cyclooxygenase enzymes, making it effective for relieving pain, reducing fever, and controlling inflammation.
Due to its pharmacological activity and solubility profile, it is used in pharmaceutical preparations, particularly in effervescent tablets and injectable formulations. Additionally, sodium salicylate finds use in cosmetic formulations, dyes, and as an intermediate in chemical synthesis. Its anti-inflammatory effect and compatibility with other active substances make it a versatile ingredient in various sectors.
Chemical Properties
Chemical Name: Sodium Salicylate
Synonyms: Salicylic acid sodium salt
Molecular Formula: C₇H₅NaO₃
Molecular Weight: 160.1 g/mol
CAS Number: 54-21-7
EC Number: 200-198-0
Appearance: White crystalline powder, granules, or aqueous solution
Odor: Odorless
Solubility: Easily soluble in water, slightly soluble in alcohol
Density: ~1.44 g/cm³
pH (1% solution): ~6.5–7.5
Melting Point: ~200°C
Forms Available: Powder, granules, liquid
Biodegradability: Not classified as readily biodegradable
Regulatory Compliance: REACH, FDA, USP, Ph. Eur., GHS
Applications
Pharmaceuticals: Analgesic, antipyretic, and anti-inflammatory agent
Cosmetics & Personal Care: Anti-acne and exfoliating ingredient
Chemical Synthesis: Intermediate in organic compound production
Dye and Pigment Industry: Stabilizer and auxiliary reagent
Veterinary Medicine: Anti-inflammatory agent in livestock products
Industries of Use
Pharmaceuticals & Medicine:
Sodium salicylate is widely used in the treatment of rheumatic disorders, fever, and headaches. It is a preferred NSAID where aspirin sensitivity is an issue. Its solubility makes it suitable for oral and parenteral drug forms.
Cosmetic Formulations:
It serves as a mild exfoliant and anti-inflammatory agent in skin care products such as lotions, creams, and cleansers targeting acne and blemishes.
Chemical Industry:
Used as a precursor and stabilizer in various organic syntheses and dye production, especially where a phenolic structure is required.
Veterinary Health:
It is incorporated into formulations to treat inflammation and fever in farm animals, particularly in oral liquid medications.
Storage Conditions
Store in tightly closed containers in a cool, dry, and ventilated area.
Avoid exposure to excessive heat, moisture, and direct sunlight.
Packaging
20 L HDPE drum (liquid)
200 L HDPE barrel (liquid)
25 kg bag (powder or granule)
Safety & Handling
Wear appropriate gloves, safety goggles, and protective clothing.
Avoid inhalation of dust and contact with skin or eyes.
Handle in accordance with local chemical safety regulations.
